29311-94-2

Basic information

• Product Name: 1,4-bis[(3-chloro-2-hydroxypropyl)amino]anthraquinone
• Synonyms: 1,4-bis[(3-chloro-2-hydroxypropyl)amino]anthraquinone;9, 10-Anthracenedione, 1, 4-bis[(3-chloro-2-hydroxypropyl) amino];C.I.Reactive Blue 6;Chemicyl Blue R;Simactive Navy Blue 25008.;1,4-Bis[(3-chloro-2-hydroxypropyl)amino]-9,10-anthracenedione;1,4-bis[(3-chloro-2-hydroxypropyl)amino]anthracene-9,10-dione
• CAS NO: 29311-94-2
• Molecular Formula: C₂₀H₂₀Cl₂N₂O₄
• Molecular Weight: 423.2898
• EINECS: 249-550-5
• Mol File: 29311-94-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 727.8°Cat760mmHg
• Flash Point: 394°C
• Appearance: /
• Density: 1.498g/cm³
• Vapor Pressure: 3.1E-22mmHg at 25°C
• Refractive Index: 1.699
• CAS DataBase Reference: 1,4-bis[(3-chloro-2-hydroxypropyl)amino]anthraquinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis[(3-chloro-2-hydroxypropyl)amino]anthraquinone(29311-94-2)
• EPA Substance Registry System: 1,4-bis[(3-chloro-2-hydroxypropyl)amino]anthraquinone(29311-94-2)

Safety Data

• Hazardous Substances Data: 29311-94-2(Hazardous Substances Data)

Usage

Preparation

The boiling of 1,4-Diaminoanthraquinone?was added acetic epichlorohydrin

Properties and Applications

bright blue, blue powder. Used for cotton and polyamide fabric dyeing and printing. Standard(Polyamide) Light Fastness Oxygen bleaching Persperation Fastness Soaping Fading Stain Fading Stain Fading Stain ISO 5 5 5

Standard(Polyamide)

Light Fastness

Fading

Stain

ISO

5

InChI:InChI=1/C20H20Cl2N2O4/c21-7-11(25)9-23-15-5-6-16(24-10-12(26)8-22)18-17(15)19(27)13-3-1-2-4-14(13)20(18)28/h1-6,11-12,23-26H,7-10H2

Upstream product

• 128-95-0 1,4-diamino-9,10-anthraquinone 
• 106-89-8 epichlorohydrin 

Downstream Products

• 78146-26-6 1,4-Bis-(2,3-epoxypropylamino)-9,10-anthracenedione 
• 1909226-00-1 1-<<3-(diethylamino)-2-hydroxypropyl>amino>-4-<(2,3-epoxypropyl)amino>-9,10-anthracenedione 
• 99788-75-7 1,4-bis(2,3-dihydroxypropylamino)-9,10-anthracenedione 

Relevant articles and documents

BH4 ANTAGONISTS AND METHODS RELATED THERETO

The disclosure relates to BH4 inhibitors and therapeutic uses relates thereto. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, comprising administering therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof.

Preparation of 1,4-bis(hydroxylakylamino)anthraquinones as protein kinase C inhibitors.

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Novel Non-Cross Resistant Diaminoanthraquinones as Potential Chemotherapeutic Agents

A novel series od diaminoanthraquinones was discovered initially as protein kinase C inhibitors with IC50s in the 50-100 μM range.They exhibited potent tumor cell growth inhibitory activity in vitro without cross resistance to adriamycin.Further evaluation of two of the most active compounds NSC 639365 (3) and NSC 639366 (4) in human tumor cloning assay showed potent cytocidal activity.The results suggest therapeutical potentials against human tumors.