293301-09-4Relevant articles and documents
3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase
Thompson,Connolly,Hamby,Boushelle,Hartl,Amar,Kraker,Driscoll,Steinkampf,Patmore,Vincent,Roberts,Elliott,Klohs,Leopold,Showalter,Denny
, p. 4200 - 4211 (2007/10/03)
A series of 3-aryl-1,6-naphthyridine-2,7-diamines and related 2-ureas were prepared and evaluated as inhibitors of the FGF receptor-1 tyrosine kinase. Condensation of 4,6-diaminonicotinaldehyde and substituted phenylacetonitriles gave intermediate naphthy