293307-62-7Relevant academic research and scientific papers
Palladium-catalyzed oxidative carbonylation of N-allylamines for the synthesis of β-lactams
Li, Wu,Liu, Chao,Zhang, Heng,Ye, Keyin,Zhang, Guanghui,Zhang, Wangzheng,Duan, Zhengli,You, Shuli,Lei, Aiwen
supporting information, p. 2443 - 2446 (2014/03/21)
β-Lactam scaffolds are considered to be ideal building blocks for the synthesis of nitrogen-containing compounds. A new palladium-catalyzed oxidative carbonylation of N-allylamines for the synthesis of α-methylene-β- lactams is reported. DFT calculations suggest that the formation of β-lactams via a four-membered-ring transition state is favorable. Four corners: The β-lactam scaffold is considered to be an ideal building block for the synthesis of nitrogen-containing compounds. A new, simple, and convenient palladium-catalyzed oxidative carbonylation of N-allylamines for the synthesis of α-methylene-β-lactams is reported. DFT calculations suggest that the formation of the β-lactam via a four-membered-ring transition state is favorable. Copyright
Synthesis of Optically Active α-Methylene β-Lactams through Lipase-Catalyzed Kinetic Resolution
Adam, Waldemar,Groer, Peter,Humpf, Hans-Ulrich,Saha-Moeller, Chantu R.
, p. 4919 - 4922 (2007/10/03)
A convenient method for the preparation of the hitherto unknown chiral α-methylene β-lactam derivatives 5a,b is reported. The optically active α-methylene β-lactams 5a-c, and their corresponding amino acids 6a-c have been readily made available through li
