293329-56-3

Upstream product

• 293329-57-4 1-(2,2-dimethoxyethyl)-6-oxo-2-phenyl-1,6-dihydropyrimidin-5-ylcarboxylic acid 
• 543-27-1 isobutyl chloroformate 
• 108-20-3 di-isopropyl ether 

Downstream Products

• 293329-58-5 N-acetyloxy-1-(2,2-dimethoxyethyl)-6-oxo-2-phenyl-1,6-dihydropyrimidin-5-ylcarboxamide 
• 337969-31-0 N-[(1S)-2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-1-(methylethyl)-2-oxoethyl]-2-{6-oxo-2-phenyl-5-[(phenylmethoxy)carbonylamino]hydropyrimidinyl}acetamide 
• 293329-59-6 5-amino-1-(2,2-dimethoxyethyl)-6-oxo-2-phenyl-1,6-dihydropyrimidine 
• 293329-60-9 [5-[(benzyloxycarbonyl)amino]-2-phenyl-6-oxo-1,6-dihydro-1-pyrimidinyl]acetaldehyde dimethyl acetal 
• 148747-59-5 5-benzyloxycarbonylamino-6-oxo-2-phenyl-1,6-dihydropyrimidin-1-ylmethylcarboxylic acid 
• 148747-58-4 [5-[(benzyloxycarbonyl)amino]-2-phenyl-6-oxo-1,6-dihydro-1-pyrimidinyl]acetaldehyde 

Relevant academic research and scientific papers

Improved synthesis of a new nonpeptidic inhibitor of human neutrophil elastase

A practical method for the synthesis of ONO-6818 {2-(5-Amino-6-oxo-2-phenylhydropyrimidinyl)-N-[2-(5-tert-butyl-1,3,4-oxadiazo l-2-yl)-1-(methylethyl)-2-oxoethyl]acetamide} (1), the first clinical candidate for a nonpeptidic orally active inhibitor of hum

1,3,4-oxadiazole derivatives and process for producing the same

Oxadiazole derivatives represented by formula (I): (wherein R1represents a hydrogen atom or an amino-protective group; R2, R3, and R4each independently represents an alkyl group, a cycloalkyl group, a phenyl gro

PYRIMIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF

Novel pyrimidine derivatives represented by formula (I): (wherein R1 represents a (in the group, R3 represents a leaving group), a hydroxycarbamoyl group, or an amino group; and R2 represents a group capable of converting