2935-91-3

Upstream product

• 2935-95-7 β-Propiothiolactone 
• 100-46-9 benzylamine 
• 54671-98-6 Bis(β-benzylcarbamoylethyl)trisulfid 
• 1119-62-6 3,3'-dithiobis(propionic acid) 
• 1002-18-2 3-(2-chlorocarbonyl-ethyldisulfanyl)-propionyl chloride 

Downstream Products

• 21277-97-4 2-benzyl-2H-isothiazol-3-one 
• 26542-22-3 5-chloro-2-benzyl-2H-isothiazol-3-one 
• 26542-27-8 4,5-dichloro-2-benzyl-3-isothiazolone 
• 103367-25-5 N-Benzyl-3-<<2-(benzylcarbamoyl)ethyl>sulfonylthio>propionamid 
• 68449-78-5 3-(N-benzylamino)isothiazole 
• 642087-92-1 N-benzyl-5-chloro-isothiazol-3-amine 
• 642088-24-2 N-benzylisothiazol-3-amine 1,1-dioxide 
• 642088-59-3 N-benzyl-4-bromoisothiazol-3-amine 1,1-dioxide 
• 642088-40-2 N-benzyl-5-chloroisothiazol-3-amine 1,1-dioxide 
• 26530-06-3 2-benzyl-4-isothiazolin-3-one hydrochloride salt 
• 1202071-07-5 C₁₀H₈ClNOS 
• 1202071-10-0 C₁₀H₈BrNOS 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of isothiazolyl oxazolidinones and analogous 3(2H)-isothiazolones

The synthesis and antibacterial activity of several new 5-((3-oxoisothiazol-2(3H)-yl)methyl)-3-phenyloxazolidin-2-ones 8 and analogous 2-(4-substituted phenyl)-3(2H)-isothiazolones 3 and 4 substituted at 4 and/or 3-positions of the phenyl moiety with different groups of which some have shown to increase the antibacterial activity of both 3-aryl-2-oxazolidinones and 3(2H)-isothiazolones is described. The most active compounds were isothiazolyl oxazolidinones 8a,j with unsubstituted and 8b with 4-F substituted phenyl rings which showed activities higher than analogous 3(2H)-isothiazolones and comparable or superior to linezolid, vancomycin, and ciprofloxacin against some tested microorganisms. The change in position of F and/or the use of larger substituents gave compounds with reduced or no activity. Evaluation of cytotoxicity to mouse fibroblast (NIH/3T3) cells indicated that these compounds exhibit antibacterial activity at non-cytotoxic concentrations.

Synthesis and antibacterial activity of 2-(4-substituted phenyl)-3(2H)-isothiazolones

Several new and known 2-(4-substituted phenyl)-3(2H)-isothiazolone derivatives with or without chloro substituent at C-5 position were synthesized and their in vitro antibacterial activity against selected Gram-negative and Gram-positive bacteria were eva

Oxidations of Thiocarbamidates, 10. - α-Carbamoyl Sulfoxides and Sulfones, 2.- Formation of Thiosulfonates by Hydrolysis of Cyclic α-Carbamoyl Sulfoxides

Thiosulfonates of type 12 and 14 were isolated after hydrolysis of cyclic α-carbamoyl sulfoxides of the thiazine type 1 and the thiazolidine type 4, respectively.Structures were confirmed by spectra and independent syntheses.