293759-48-5Relevant articles and documents
Metal-Free C-C Coupling of an Allenyl Sulfone with Picolyl Amides to Access Vinyl Sulfones via Pyridine-Initiated in Situ Generation of Sulfinate Anion
Omer, Humair M.,Liu, Peng,Brummond, Kay M.
, p. 7959 - 7975 (2020/07/15)
Vinyl sulfones are privileged motifs known for their biological activity and synthetic utility. Synthetic transformations to efficiently access high-value compounds with these motifs are desired and sought after. Herein, a new procedure is described to fo
Combining metabolite-based pharmacophores with Bayesian machine learning models for mycobacterium tuberculosis drug discovery
Ekins, Sean,Madrid, Peter B.,Sarker, Malabika,Li, Shao-Gang,Mittal, Nisha,Kumar, Pradeep,Wang, Xin,Stratton, Thomas P.,Zimmerman, Matthew,Talcott, Carolyn,Bourbon, Pauline,Travers, Mike,Yadav, Maneesh,Freundlich, Joel S.
, (2015/12/26)
Integrated computational approaches for Mycobacterium tuberculosis (Mtb) are useful to identify new molecules that could lead to future tuberculosis (TB) drugs. Our approach uses information derived from the TBCyc pathway and genome database, the Collabor
