294173-01-6

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 99264-74-1 H-D-Ala-Phe-Lys-OH 

Downstream Products

• 791574-88-4 {(S)-5-[(S)-2-((R)-2-Benzyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-5-[methyl-(2-methylamino-ethyl)-carbamoyl]-pentyl}-carbamic acid benzyl ester 
• 767275-91-2 [(S)-5-[(S)-2-((R)-2-Benzyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-5-(2-methylamino-ethylcarbamoyl)-pentyl]-carbamic acid benzyl ester 
• 294173-07-2 Z-D-Ala-Phe-Lys(Z)-NH-(CH₂)2-N(Me)-Boc 
• 294173-06-1 Z-D-Ala-Phe-Lys(Z)-N(Me)-(CH₂)2-N(Me)-Boc 
• 99264-74-1 H-D-Ala-Phe-Lys-OH 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 2'-carbamate-linked and 2'-carbonate-linked prodrugs of paclitaxel selective activation by the tumor-associated protease plasmin

The nontoxic paclitaxel-2'-carbamate prodrugs 2-5 and paclitaxel-2'-carbonate prodrug 6 were synthesized and tested for activation by the tumor-associated enzyme plasmin. A generally applicable method for the synthesis of paclitaxel-2'-carbamates was deve

Low molecular peptides as potential inhibitors of plasmin

Ten peptides of the general formula A-Phe-Lys-X where A = H, H-D-Val, H-L-Val, H-D-Ala, H-L-Ala and X = OH, NH2 were obtained and tested for their antiplasmin activity with the use of amidolytic test.