294196-07-9 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
(S)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE is used as a key compound in pharmaceutical research and drug development for its potential therapeutic effects. Its unique chemical structure and properties make it a valuable asset in the creation of new drugs with improved efficacy and safety profiles.
Used in Serotonin Receptor Antagonist Development:
In the field of neurological and psychiatric disorders, (S)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE is used as a potential serotonin receptor antagonist. Its activity in this area could lead to the development of novel treatments for a range of conditions, including anxiety, depression, and other mood disorders.
Used in Understanding Structure-Activity Relationships:
(S)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE is employed as a model compound in the study of structure-activity relationships within the benzoazepine class. This helps researchers to better understand how the compound's structure influences its biological activity, which can inform the design of more effective drugs targeting the serotonin receptor system.
Used in the Development of New Drugs Targeting the Serotonin Receptor System:
(S)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE is utilized as a starting point for the development of new drugs that target the serotonin receptor system. Its unique properties and potential as a serotonin receptor antagonist make it an important molecule in the quest to create more effective treatments for neurological and psychiatric disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 294196-07-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,4,1,9 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 294196-07:
(8*2)+(7*9)+(6*4)+(5*1)+(4*9)+(3*6)+(2*0)+(1*7)=169
169 % 10 = 9
So 294196-07-9 is a valid CAS Registry Number.
294196-07-9Relevant academic research and scientific papers
Enantioselective synthesis of the metabolites of vasopressin V2 receptor antagonist OPC-31260 via lipase-catalyzed transesterification
Matsubara, Jun,Kitano, Kazuyoshi,Otsubo, Kenji,Kawano, Yoshikazu,Ohtani, Tadaaki,Bando, Masahiko,Kido, Masaru,Uchida, Minoru,Tabusa, Fujio
, p. 4667 - 4682 (2007/10/03)
The optical isomers of 5-dimethylamino-1-[4-(2- methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine (OPC-31260, 1) and its metabolites (2, 3, 4, 5 and 6) were enantioselectively synthesized. The chiral acetate 8b and alcohol 7a were prepared via the resolution of the racemic alcohol (±)-7 using the lipase-mediated transesterification in vinyl acetate. The compounds 8b and 7a were converted to the hydroxy metabolites (2a and 2b), the methylamine metabolites (3a and 3b), the dimethylamines (1a and 1b), and the amine metabolites (4a and 4b) in several steps while maintaining their absolute configurations. The 4,5-diol metabolites (5a, 5b, 6a and 6b) were synthesized from the key intermediates obtained by the lipase-catalyzed transesterification. (C) 2000 Elsevier Science Ltd.
