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(R)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE, a cyclic amine with the molecular formula C13H17N, is a member of the benzazepine class of heterocyclic compounds. This chemical compound features a rigid, tricyclic structure that may contribute to unique pharmacological properties. Its structural resemblance to neurotransmitters and potential receptor activity in the central nervous system make it a promising candidate for medical research and pharmaceutical development.
Used in Pharmaceutical Development:
(R)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE is used as a chemical intermediate for the synthesis of various pharmaceuticals due to its potential activity on receptors in the central nervous system. Its unique structure may lead to the development of new drugs with novel mechanisms of action.
Used in Medical Research:
In the field of medical research, (R)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE is used as a research tool to study the interactions between neurotransmitters and their receptors. Its structural similarity to certain neurotransmitters allows researchers to investigate the underlying mechanisms of various neurological disorders and develop targeted therapeutic interventions.
Used in Drug Design and Optimization:
(R)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE is used as a lead compound in drug design and optimization processes. Its tricyclic structure provides a foundation for the development of new drugs with improved pharmacokinetic and pharmacodynamic properties. By modifying its chemical features, researchers can optimize its binding affinity, selectivity, and efficacy for specific therapeutic targets.
Used in Neurotransmitter Research:
In the study of neurotransmitters, (R)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE is used as a reference compound to understand the structure-activity relationships of neurotransmitters and their receptors. This knowledge can be applied to design drugs that modulate neurotransmission, potentially treating a range of neurological and psychiatric disorders.
Used in Drug Discovery:
(R)-(2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YL)AMINE is used as a starting point in drug discovery efforts, particularly for the development of new central nervous system (CNS) active agents. Its unique pharmacological properties and potential receptor interactions make it a valuable compound for exploring novel therapeutic avenues in the treatment of CNS disorders.

294196-60-4

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294196-60-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 294196-60-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,4,1,9 and 6 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 294196-60:
(8*2)+(7*9)+(6*4)+(5*1)+(4*9)+(3*6)+(2*6)+(1*0)=174
174 % 10 = 4
So 294196-60-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2/c11-9-5-3-7-12-10-6-2-1-4-8(9)10/h1-2,4,6,9,12H,3,5,7,11H2/t9-/m1/s1

294196-60-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (5R)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-amine

1.2 Other means of identification

Product number -
Other names S14-2553

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:294196-60-4 SDS

294196-60-4Upstream product

294196-60-4Relevant academic research and scientific papers

Enantioselective synthesis of the metabolites of vasopressin V2 receptor antagonist OPC-31260 via lipase-catalyzed transesterification

Matsubara, Jun,Kitano, Kazuyoshi,Otsubo, Kenji,Kawano, Yoshikazu,Ohtani, Tadaaki,Bando, Masahiko,Kido, Masaru,Uchida, Minoru,Tabusa, Fujio

, p. 4667 - 4682 (2007/10/03)

The optical isomers of 5-dimethylamino-1-[4-(2- methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine (OPC-31260, 1) and its metabolites (2, 3, 4, 5 and 6) were enantioselectively synthesized. The chiral acetate 8b and alcohol 7a were prepared via the resolution of the racemic alcohol (±)-7 using the lipase-mediated transesterification in vinyl acetate. The compounds 8b and 7a were converted to the hydroxy metabolites (2a and 2b), the methylamine metabolites (3a and 3b), the dimethylamines (1a and 1b), and the amine metabolites (4a and 4b) in several steps while maintaining their absolute configurations. The 4,5-diol metabolites (5a, 5b, 6a and 6b) were synthesized from the key intermediates obtained by the lipase-catalyzed transesterification. (C) 2000 Elsevier Science Ltd.

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