294211-63-5Relevant articles and documents
Stereochemically controlled synthesis of 1,8-dioxaspiro[4.5]decanes and 1-oxa-8-thiaspiro[4.5]decanes by phenylsulfanyl migration
Earnes, Jason,Fox, David J.,De Las Heras, Maria A.,Warren, Stuart
, p. 1903 - 1914 (2007/10/03)
Single enantiomers and diastereoisomers of 2- and 3-alkyl-3-phenylsulfanyl-1,8-dioxa- and 1-oxa-8-thiaspiro-[4.5]decanes can be prepared in good yield by acid-catalysed phenylsulfanyl (PhS-) migration. Either the syn-or anti-stereochemistry can be controlled by aldol reactions or by reduction of hydroxy-ketones. The Royal Society of Chemistry 2000.