29433-95-2Relevant articles and documents
Preparation method of carbocisteine
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Paragraph 0022; 0023; 0024; 0025; 0026; 0027; 0028-0040, (2017/06/02)
The invention discloses a preparation method of carbocisteine. The preparation method comprises the three steps of condensation reaction, neutralization and crystallization, and recrystallization. Through adding carbonate and an antioxidant to a reaction system and strictly controlling reaction conditions, the content of impurity amino acid in a finished product is reduced substantially, and the purity and the product quality of carbocisteine are improved. The preparation method has the advantages of simplicity in operation, short production cycle, low cost, and the like.
A process for preparing carbocysteine (by machine translation)
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Paragraph 0025; 0026, (2017/01/12)
The invention discloses a process for preparing a compound, in particular to a process for preparing carbocysteine, which belongs to the field of organic synthetic technology; the [...] erdosteine preparation process, comprising the following steps: (a) taking L - cysteine hydrochloride monohydrate and solid chlorine acetic acid, wherein the chloroacetic acid to L - cysteine hydrochloride monohydrate quality of 60 - 70%-out, (b) the L - cysteine hydrochloride monohydrate and sodium monochloroacetate stirring to dissolve in the water, the dissolution process of the control system temperature is 15 - 25 °C, (c) of the system is adjusted to PH 7.0 - 7.5, control system temperature is 45 - 50 °C, mixing and reaction, (d) after the completion of the reaction, of the system is adjusted to PH 6.0 - 6.4, to decolorize the, absorb the impurity processing, (e) filtering, regulate filtrate of PH to 2.8 - 3.0, cooling and getting the wound and crystallization; the process route is prepared carbocysteine, has high purity, high yield, good stability, and simple process route, easy to operate and control. (by machine translation)
S-carboxymethylcysteine synthase from Escherichia coli
Kumagai,Suzuki,Shigematsu,Tochikura
, p. 2481 - 2487 (2007/10/02)
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