29462-22-4

Upstream product

• 4702-13-0 N-phthaloylglycine 
• 29462-26-8 LUF₅₅₃₂ 
• 41042-88-0 glycine 3-(2-chloro-benzoyl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylamide 

Downstream Products

• 49682-38-4 5-(2-chloro-phenyl)-1,3,6,7,8,9-hexahydro-benzo[4,5]thieno[2,3-e][1,4]diazepine-2-thione 
• 50509-59-6 5-(2-chloro-phenyl)-1-methyl-1,3,6,7,8,9-hexahydro-benzo[4,5]thieno[2,3-e][1,4]diazepin-2-one 
• 40054-79-3 6-(2-chloro-phenyl)-1-methyl-7,8,9,10-tetrahydro-4H-benzo[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine 
• 67727-31-5 5-(2-chloro-phenyl)-1,3,6,7,8,9-hexahydro-benzo[4,5]thieno[2,3-e][1,4]diazepin-2-one acetylhydrazone 

Relevant academic research and scientific papers

Synthesis and pharmacological evaluation of 2,3 dihydro 1H thieno[2,3 e][1,4]diazepines

A series of 2,3 dihydro 1H thieno[2,3 e][1,4]diazepines was synthesized and evaluated for CNS activity. A new antianxiety screen for benzodiazepine like drugs was used along with the standard anticonvulsant test. Structure activity relationships are discussed. One compound, 1,3,6,7,8,9 hexahydro 5 phenyl 2H [1]benzothieno[2,3 e][1,4]diazepin 2 one monosulfate (CI 718), is undergoing clinical studies in man.