294664-45-2

Upstream product

• 228399-02-8 2,5-anhydro-3,6-di-O-benzoyl-4-O-methanesulfonyl-D-allose ethylene acetal 
• 157506-37-1 2,5-anhydro-4,6-di-O-benzoyl-3-O-methanesulfonyl-D-glucose ethylene acetal 
• 228399-00-6 2,5-anhydro-3,6-di-O-benzoyl-D-allose ethylene acetal 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 294664-44-1 C₂₁H₂₀O₉S 

Downstream Products

• 294664-46-3 3(5)-carbomethoxy-4-(2,5-di-O-benzoyl-3-O-methanesulfonyl-β-D-ribofuranosyl)pyrazole 

Relevant academic research and scientific papers

Stereospecific synthesis of two novel cytotoxic pyrazole C-nucleosides from D-glucose

A multistep stereospecific synthesis of two novel pyrazole C-nucleosides 12 and 21 has been achieved starting from D-glucose, by utilizing the 2,5- anhydro-D-glucose ethylene acetal derivative 1 as a divergent intermediate. The C-nucleoside 12 was shown to be a moderate inhibitor of the in vitro growth of N2a and BHK 21 tumor cell lines, whereas 21 showed a moderate cytotoxic activity only against N2a cells. (C) 2000 Published by Elsevier Science Ltd.