294664-69-0

Upstream product

• 264198-10-9 (2S,2'R,5'S,1''S)-2-Benzyloxycarbonylamino-3-[5'-(1''-tert-butoxycarbonylaminoethyl)tetrahydrofuran-2'-carbamoyl] methyl propionate 
• 35761-27-4 methyl (2S)-3-amino-2-{[(benzyloxy)carbonyl]amino}propanoate hydrochloride 
• 259091-45-7 (2R,5S,1'S)-5-{1'-[(tert-butoxycarbonyl)amino]ethyl}tetrahydrofuran-2-carboxylic acid 

Downstream Products

• 264198-18-7 {N-(tert-Butoxycarbonyl)glycyl}-{(2'R,5'S,1''S)-5'-(1''-aminoethyl)tetrahydrofuran-2'-carbonyl}-{(2S)-3-amino-2-benzyloxycarbonylamino methyl propionate} 
• 264198-19-8 C₃₂H₄₈N₆O₁₁ 

Relevant academic research and scientific papers

Synthesis and biological evaluation of integrin antagonists containing trans- and cis-2,5-disubstituted THF rings

The synthesis of a series of RGD mimetics is described. All compounds consist of a central 2,5-disubstituted tetrahydrofuran core, a variable linker to a guanidino group, and a β-amino alanine unit to mimic the carboxylic acid. Three types of linkers were