29528-17-4Relevant academic research and scientific papers
Synthesis method of amino substituted 2-phenylbenzimidazole derivative
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Paragraph 0025-0026, (2018/09/21)
The invention relates to a synthesis method of an amino substituted 2-phenylbenzimidazole derivative. The method uses cheap and easily available nitro substituted benzoic acid compound and dinitraniline compound as the raw materials for condensation to obtain an amide compound, then catalytic hydrogenation is carried out, and simultaneously cyclization is conducted to obtain the benzimidazole derivative. The reaction is green and efficient, the operation is simple and the yield is excellent.
