295311-40-9

Upstream product

• 350-19-6 ethyl 3,5-difluorobenzoate 
• 110-91-8 morpholine 
• 216393-55-4 methyl 3,5-difluorobenzoate 
• 220954-16-5 3-fluoro-5-morpholinobenzonitrile 
• 936801-44-4 (3-fluoro-5-morpholinophenyl)(morpholino)methanone 

Downstream Products

• 295311-58-9 N-(4-fluoro-3-nitrophenyl)-3-fluoro-5-morpholinobenzamide 
• 884340-51-6 3-fluoro-5-morpholinobenzoyl chloride 
• 874133-54-7 3-fluoro-5-morpholin-4-yl-N-[4-(3-morpholin-4-yl-propenyl)-naphthalen-2-yl]-benzamide 
• 1240423-98-6 3-fluoro-5-(morpholin-4-yl)-N-[2-(tritylsulfanyl)benzyl]benzamide 
• 1006584-06-0 C₂₆H₃₄FN₃O₅ 
• 942999-25-9 N-(tert-butyloxycarbonyl)-3-fluoro-5-(4-morpholinyl)aniline 
• 874133-41-2 N-(4-bromo-naphthalen-1-yl)-3-fluoro-5-morpholin-4-yl-benzamide 
• 943641-22-3 N-(5-acetyl-6-methylpyridin-3-yl)-3-fluoro-5-morpholinobenzamide 

Relevant academic research and scientific papers

HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS

The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cyt

HETEROCYCLIC CYTOKINE INHIBITORS

The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory, anti-pain or anti-cancer agents. There are further provided m

BISAMIDE CYTOKINE INHIBITORS

The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are bisamides and are useful as anti-inflammatory agents. In one aspect the compounds have the

THIOPHENE AMIDE COMPOUNDS FOR USE IN THE TREATMENT OR PROPHYLAXIS OF CANCERS

The invention provides the use of a compound for the manufacture of a medicament for the prophylaxis or treatment of a cancer or a para-neoplastic effect associated with a cancer, the para-neoplastic effect being other than cachexia, and the compound bein

1,4-DISUBSTITUTED NAPHTALENES AS INHIBITORS OF P38 MAP KINASE

In general, the present invention relates to compounds capable of inhibiting P38, methods for inhibiting P38 in vivo or in vitro, diagnostics for determining activity in the treatment of P38 and/or cytokine-associated conditions and methods for treating c

5-MORPHOLINYLMETHYLTHIOPHENYL PHARMACEUTIAL COMPOUNDS AS P38 MAP KINASE MODULATORS

The invention provides compounds of the formula (I) or a salt, solvate or N-oxide thereof, wherein:R1 and R2 are the same or different and each is selected from hydrogen, saturated C1-3 hydrocarbyl, halogen and cyano; X is

5-AMINO-2-CARBONYLTHIOPHENE DERIVATIVES FOR USE AS P38 MAP KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATORY DISEASES

The invention provides the use of a compound for the manufacture of a medicament for the prophylaxis or treatment of a disease state or condition mediated by a p38 MAP kinase; the compound being defined by formula (I): wherein: R1 and R2/

AMIDE DERIVATIVES

The invention concerns amide derivatives of Formula (Ia) wherein X is -NHCO- or -CONH-; m is 0-3; R1 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; n is 0-2; R2 is a group