295357-45-8Relevant academic research and scientific papers
Reaction of peroxyacetals with silyl ketene acetals: Synthesis of 3- peroxyalkanoates and 3-peroxyalkanals
Dussault,Lee,Schultz,Suh
, p. 5457 - 5460 (2000)
Lewis acid-mediated reaction of monoperoxyacetals with silyl ketene acetals (SKAs) provides an efficient approach to 3-peroxyalkanoates. Propionate SKAs react with aliphatic peroxyacetals to furnish 3-peroxy-2- methyl alkanoates with modest anti-selectivity. Although acetate and thioacetate SKAs are less reactive, the latter react with unsaturated peroxyacetals to furnish peroxyalkenoates and -alkadienoates which undergo chemoselective reduction to 3-peroxyalkenals and 3-peroxyalkadienals. (C) 2000 Elsevier Science Ltd.
