29545-47-9 Usage
Uses
Used in Pharmaceutical Industry:
12-DOXYLSTEARIC ACID is used as a competitive inhibitor for lipoxygenase due to its high affinity, with a Ki of 9 .mu.M. This makes it a valuable compound in the development of drugs targeting lipoxygenase-related pathways, which can be beneficial in treating various inflammatory and allergic conditions.
Used in Research and Development:
In the field of research and development, 12-DOXYLSTEARIC ACID serves as an essential tool for studying the interactions between fatty acids and lipoxygenase enzymes. Its spin-labeled nature allows for detailed investigations into the enzyme's structure, function, and inhibition mechanisms, contributing to a better understanding of related biological processes.
Used in Analytical Chemistry:
12-DOXYLSTEARIC ACID, being a spin-labeled fatty acid, is utilized in analytical chemistry for the detection and quantification of lipoxygenase activity. Its unique properties enable the development of sensitive and specific assays, which can be employed in quality control, diagnostics, and monitoring of enzyme activity in various samples.
Used in Drug Design and Development:
The competitive inhibition properties of 12-DOXYLSTEARIC ACID make it a promising candidate for drug design and development, particularly in the creation of novel therapeutic agents targeting lipoxygenase. Its high affinity and specificity for the enzyme can be leveraged to develop more effective and targeted treatments for conditions involving lipoxygenase dysregulation.
Check Digit Verification of cas no
The CAS Registry Mumber 29545-47-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,5,4 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 29545-47:
(7*2)+(6*9)+(5*5)+(4*4)+(3*5)+(2*4)+(1*7)=139
139 % 10 = 9
So 29545-47-9 is a valid CAS Registry Number.
InChI:InChI=1/C22H42NO4/c1-5-6-15-19(2)22(23(26)21(3,4)18-27-22)17-14-12-10-8-7-9-11-13-16-20(24)25/h19H,5-18H2,1-4H3,(H,24,25)
29545-47-9Relevant academic research and scientific papers
Improved yields in the synthesis of spin-labeled fatty acids
Mravljak, Janez,Pecar, Slavko
, p. 3763 - 3771 (2007/10/03)
Paramagnetic amide side products (6a-g) have been isolated from the reaction mixture in the synthesis of spin-labeled fatty acids of the doxyl type. After their hydrolysis to the corresponding acid, 7, the overall yield of spin-labeled fatty acids is significantly increased compared with published procedures.
