29588-03-2Relevant articles and documents
Simple and Efficient Synthesis of 5-Substituted-3-phenyl-2-thioxoimidazolidin-4-one Derivatives from S -Amino Acids and Phenylisothiocyanate in et 3N/DMF-H 2O
Jangale, Asha D.,Wagh, Yogesh B.,Tayade, Yogesh A.,Dalal, Dipak S.
supporting information, p. 1876 - 1886 (2015/08/03)
A concise approach for the transformation of various S-amino acids into the 5-alkyl-3-phenyl-2-thioxoimidazolidin-4-one heterocycles using phenylisothiocyanate is described. Phenylthiohydantoins of amino acid were synthesized at room temperature in Et3N/DMF-H2O with easy workup and excellent yields.