2961-80-0

Usage

Uses

Used in Organic Synthesis:
Cyclopropene-3-one is used as a building block for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Its reactivity and ability to participate in cycloaddition reactions make it a versatile component in the creation of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Cyclopropene-3-one is used as a key intermediate in the synthesis of various drug molecules. Its unique structure and reactivity allow for the development of new and innovative therapeutic agents.
Used in Agrochemical Industry:
Cyclopropene-3-one is also utilized in the agrochemical industry for the synthesis of pesticides and other crop protection agents. Its reactivity enables the creation of novel compounds with improved efficacy and selectivity.
Used in Research and Development:
Due to its unique properties, Cyclopropene-3-one is a valuable reagent in academic and industrial research settings. It is used to explore new reaction pathways, develop innovative synthetic methods, and study the mechanisms of various chemical transformations.

InChI:InChI=1/C3H2O/c4-3-1-2-3/h1-2H

Upstream product

• 23529-83-1 3,3-dimethoxycyclopropene 
• 40301-85-7 1,4-bis-diazo-butane-2,3-dione 
• 108-31-6 maleic anhydride 
• 141245-07-0 (6,6-Dimethyl-4,8-dioxa-spiro[2.5]oct-1-en-1-yl)-trimethyl-silane 
• 6262-42-6 1,2,3,3-tetrachlorocyclopropene 

Downstream Products

• 74-86-2 acetylene 

Relevant academic research and scientific papers

Experimental and theoretical study of the photochemical and thermal decomposition of maleic and dichloromaleic anhydrides

The photochemical and thermal behavior of maleic anhydride 1a and dichloromaleic anhydride 1b, in cryogenic matrix were investigated by means of FT-IR spectroscopy. The ketenylcarbenes represent the key intermediate in the decomposition processes of the a

Cyclopropenones in the synthesis of indolizidine, pyrrolo[2,1-a]isoquinoline and indolizino[8,7-b]indole alkaloids

An attempted synthesis of the indolizidine natural product castanospermine resulted in the successful addition of cyclopropenone to a sugar-derived poly-hydroxylated cyclic imine to give an indolizidinone product, but with the installation of an extra hydroxy group at the castanospermine 8a-bridgehead position. This was also observed in our previous approach to the australine and hyacinthacine pyrrolizidine natural products. The same oxidative phenomenon occurred during the synthesis of pyrrolo[1,2-a]isoquinolines from the reaction of aldimine dihydroisoquinolines with cyclopropenones, whereas ketimine based dihydroisoquinolines gave pyrrolo[1,2-a]isoquinolines without bridgehead oxidation. These results may have some significance for the origins of the bridgehead hydroxy natural products jenamidine B1/B2, clazamycin A/B and legonmycin A/B. The precursor cyclic aldimine for the synthesis of the indolizino[8,7-b]indoles gave dimeric indolizino[8,7-b]indoles, whereas the corresponding cyclic ketimines behaved as expected and gave the indolizino[8,7-b]indole core after reaction with cyclopropenones.

GENERAL SYNTHESIS OF CYCLOPROPENONES AND THEIR ACETALS

Metalated cyclopropenone acetals 5 react with a variety of electrophiles, including alkyl halides, carbonyl compounds, vinyl iodides, vinyl triflates, and aryl iodides, to give substituted cyclopropenone acetals in high yield.Hydrolysis of the acetal unde

Small Rings, 41. Oxirene: Intermediate or Transition State? Matrix Irradiation of Diazoketones

On irradiation of diazoketones - even of those which do not undergo a Wolff rearrangement under standard conditions - in an argon matrix at 10 K oxirenes (or acylcarbenes) cannot be detected directly.