296253-32-2

Upstream product

• 293751-07-2 1-(3-O-benzyl-2,5-di-O-methanesulfonyl-4-C-(methanesulfonyloxymethyl)-β-D-erythro-pentofuranosyl)thymine 
• 293751-06-1 1-(3-O-benzyl-5-O-methanesulfonyl-4-C-methanesulfonyloxymethyl-β-D-erythro-pentofuranosyl)thymine 
• 293751-08-3 (1S,3R,4S,7S)-7-benzyloxy-1-(methanesulfonyloxymethyl)-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane 
• 293751-09-4 (1R,3R,4S,7S)-7-benzyloxy-1-(hydroxymethyl)-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 284497-22-9 (1R,3R,4S,7S)-7-hydroxy-1-(hydroxymethyl)-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane 

Relevant academic research and scientific papers

Convenient Syntheses of 7-Hydroxy-1-(hydroxymethyl)-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptanes: α-L-Ribo- and α-L-Xylo-Configured LNA Nucleosides

Synthesis of the diastereoisomeric LNA (locked nucleic acid) nucleosides 1-(2-O,4-C-methylene-α-L-ribofuranosyl)thymine (6) and 1-(2-O,4-C-methylene-α-L-xylofuranosyl)thymine (13) are reported via convenient reaction cascades from di-O-p-toluenesulfonyl and tri-O-methanesulfonyl nucleoside derivatives 3, 7, and 10.