296264-81-8

Upstream product

• 106-38-7 para-bromotoluene 
• 296264-44-3 2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-p-tolyl-pentyl ester 
• 296264-68-1 2,2-Dimethyl-propionic acid (3R,4R)-4-[2-(2,2-dimethyl-propionyloxy)-ethyl]-7-methyl-1-oxo-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl ester 
• 296264-56-7 2,2-Dimethyl-propionic acid (2R,3R)-5-(2,2-dimethyl-propionyloxy)-2-isocyanato-3-p-tolyl-pentyl ester 
• 296264-32-9 4-(2-methoxycarbonyl-1-p-tolyl-ethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 296264-76-1 10-(2-hydroxy-ethyl)-7-methyl-3-phenyl-10,10a-dihydro-1H-oxazolo[3,4-b]isoquinolin-5-one 
• 296264-74-9 (3R,4R)-4-(2-Hydroxy-ethyl)-3-hydroxymethyl-7-methyl-3,4-dihydro-2H-isoquinolin-1-one 
• 123751-09-7 tert-butyl (4R)-4-[(1E)-3-methoxy-3-oxoprop-1-en-1-yl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate 
• 296264-78-3 Methanesulfonic acid 2-((10R,10aR)-7-methyl-5-oxo-3-phenyl-1,5,10,10a-tetrahydro-oxazolo[3,4-b]isoquinolin-10-yl)-ethyl ester 

Relevant academic research and scientific papers

From serine to functionalized enantiopure tetrahydroisoquinolines

The reaction of γ-amino-α,β-unsaturated esters prepared from L-serine with diversely substituted arylcuprates affords the corresponding syn- adducts. Transformation of the amino group to an isocyanate, followed by Friedel-Crafts intramolecular condensatio