296278-03-0Relevant academic research and scientific papers
Synthesis and cytotoxic evaluation of a series of γ-substituted γ-aryloxymethyl-α-methylene-γ-butyrolactones against cancer cells
Tzeng,Lee,Wang,Han,Chen
, p. 715 - 719 (2000)
Purpose. The main objective of this investigation was to explore the cytotoxic structure-activity relationships of γ-substituted γ-aryloxy-methyl-α-methylene-γ-butyrolactones against cancer cells. Methods. The target compounds were synthesized in two step
Synthesis and1H NMR structural analysis of 11-aryl/ heteroarylnaphtha[2,1-b]furans: X-ray crystal structure of 11-(4′-pyridyl) naphtho[2,1-b]furan
Mashraqui, Sabir H.,Patil, Mamta B.,Sangvikar, Yogesh,Ashraf, Mohamed,Mistry, Hitesh D.,Daub, Elise Tran Huu,Meetsma, Auke
, p. 947 - 954 (2005)
Synthesis of biaryl type systems, 11-aryl/heteroarylnaphtho[2,1-b]furans 8-11 has been described with a view to studying the conformational orientation of C-11 aryl/heteroaryl groups. Synthesis of 8-11 was accomplished by a two-step sequence involving O-a
Cobalt-Catalyzed Reductive C-O Bond Cleavage of Lignin β-O-4 Ketone Models via in Situ Generation of the Cobalt-Boryl Species
Gao, Kecheng,Xu, Man,Cai, Cheng,Ding, Yanghao,Chen, Jianhui,Liu, Bosheng,Xia, Yuanzhi
supporting information, p. 6055 - 6060 (2020/08/12)
An efficient and mild method for reductive C-O bond cleavage of lignin β-O-4 ketone models was developed to afford the corresponding ketones and phenols with PDI-CoCl2 as the precatalyst and diboron reagent as the reductant. The synthetic utility of the methodology was demonstrated by depolymerization of a polymeric model and gram-scale transformation. Mechanistic studies suggested that this transformation involves steps of carbonyl insertion, 1,2-Brook type rearrangement, β-oxygen elimination, and rate-limiting regeneration of the catalytic active Co-B species.
Discovery of oxime-bearing naphthalene derivatives as a novel structural type of Nrf2 activators
Chang, Ken-Ming,Liang, Fong-Pin,Chen, I-Li,Yang, Shyh-Chyun,Juang, Shin-Hun,Wang, Tai-Chi,Chen, Yeh-Long,Tzeng, Cherng-Chyi
, p. 3852 - 3859 (2015/08/03)
Abstract Recent studies have demonstrated that oxidative stress insult is one of major causes of tumor formation. Therefore, identify the effective anti-oxidative agents as a preventive approach to stop cancer progression has widely explored. Although, ma
BCl3-promoted synthesis of benzofurans
Kim, Ikyon,Lee, Sei-Hee,Lee, Sunkyung
body text, p. 6579 - 6584 (2009/04/06)
Lewis acidic nature of boron trichloride (BCl3) to coordinate to the carbonyl functionality was exploited for the synthesis of benzofurans via dehydrative cyclization. This mild and efficient procedure allowed for facile access to a number of h
