29634-46-6Relevant academic research and scientific papers
The tert-butyl sulfoxide directed ortho metalation group. New synthetic methodology for substituted aromatics and pyridines and comparison with other metalation directors
Quesnelle,Iihama,Aubert,Perrier,Snieckus
, p. 2625 - 2628 (2007/10/02)
Details of the directed ortho metalation of tert-butyl phenyl sulfoxide (1) and 2- and 4-tert-butyl pyridyl sulfoxides (3a,b) are described along with comparisons with established metalation directors (CONR2, OCONR2, OMOM, SO2t-Bu) via inter- and intramolecular competition experiments.
