29669-49-6

Basic information

• Product Name: 5-Fluoro-2-thiophenecarbaldehyde
• Synonyms: 5-Fluoro-2-thiophenecarbaldehyde;5-Fluorothiophene-2-carbaldehyde;5-Fluorothiophene-2-carboxaldehyde
• CAS NO: 29669-49-6
• Molecular Formula: C₅H₃FOS
• Molecular Weight: 130.14
• Mol File: 29669-49-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Fluoro-2-thiophenecarbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Fluoro-2-thiophenecarbaldehyde(29669-49-6)
• EPA Substance Registry System: 5-Fluoro-2-thiophenecarbaldehyde(29669-49-6)

Safety Data

• Hazardous Substances Data: 29669-49-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 36, p. 2188, 1971 DOI: 10.1021/jo00814a036

Upstream product

• 824983-56-4 (5-fluorothiophen-2-yl)methanol 
• 1007388-28-4 (4-fluorothiophen-2-yl)methanol 
• 188290-36-0 thiophene 
• 400-13-5 2-fluorothiophene 
• 68-12-2 N,N-dimethyl-formamide 
• 1463484-30-1 5-fluoro-N-methoxy-N-methylthiophene-2-carboxamide 
• 4377-58-6 5-fluorothiophene-2-carboxylic acid 

Downstream Products

• 332099-22-6 ethyl 2-fluoro-4H-thieno[3,2-b]pyrrole-5-carboxylate 

Relevant articles and documents

METHODS OF TREATING PULMONARY DISEASES AND DISORDERS

The present disclosure features disclosed method of treating disorders such as COPD, bronchitis and/or asthma using disclosed compounds, optionally together with one or more additional active agents. Contemplated methods include administrating orally or by inhalation to a patient one or more disclosed compounds.

FLUORO-SUBSTITUTED INHIBITORS OF D-AMINO ACID OXIDASE

This invention provides novel inhibitors of the enzyme D-amino acid oxidase as well as pharmaceutical compositions including the compounds of the invention. The invention also provides methods for the treatment and prevention of neurological disorders, such as neuropsychiatric and neurodegenerative diseases, as well as pain, ataxia and convulsion. The compounds of the invention have the general structure: wherein A is NH or S. Q is a member selected from CR1 and N. X and Y are members independently selected from O, S, CR2, N and NH. R1, R2 and R4 are members independently selected from H and F, provided that at least one member selected from R1, R2 and R4 is F. R6 is a member selected from O?X+ and OH, wherein X+ is a positive ion, which is a member selected from inorganic positive ions and organic positive ions.