296785-20-1

Basic information

• Product Name: (2S,4R,6R)-2-[4-((E)-2-[(2R,3S,4S,5S,6R)-3,5-dimethyl-6-(2-trimethylsilyloxyethyl)-4-triphenylsilyloxy-tetrahydro-2H-pyran-2-yl]prop-1-enyl)(1,3-oxazol-2-yl)]methyl-4-methoxy-6-triethylsilyloxymethyl-tetrahydro-2H-pyran-2-ol
• Synonyms: (2S,4R,6R)-2-[4-((E)-2-[(2R,3S,4S,5S,6R)-3,5-dimethyl-6-(2-trimethylsilyloxyethyl)-4-triphenylsilyloxy-tetrahydro-2H-pyran-2-yl]prop-1-enyl)(1,3-oxazol-2-yl)]methyl-4-methoxy-6-triethylsilyloxymethyl-tetrahydro-2H-pyran-2-ol
• CAS NO: 296785-20-1
• Molecular Weight: 900.388
• Mol File: 296785-20-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,4R,6R)-2-[4-((E)-2-[(2R,3S,4S,5S,6R)-3,5-dimethyl-6-(2-trimethylsilyloxyethyl)-4-triphenylsilyloxy-tetrahydro-2H-pyran-2-yl]prop-1-enyl)(1,3-oxazol-2-yl)]methyl-4-methoxy-6-triethylsilyloxymethyl-tetrahydro-2H-pyran-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R,6R)-2-[4-((E)-2-[(2R,3S,4S,5S,6R)-3,5-dimethyl-6-(2-trimethylsilyloxyethyl)-4-triphenylsilyloxy-tetrahydro-2H-pyran-2-yl]prop-1-enyl)(1,3-oxazol-2-yl)]methyl-4-methoxy-6-triethylsilyloxymethyl-tetrahydro-2H-pyran-2-ol(296785-20-1)
• EPA Substance Registry System: (2S,4R,6R)-2-[4-((E)-2-[(2R,3S,4S,5S,6R)-3,5-dimethyl-6-(2-trimethylsilyloxyethyl)-4-triphenylsilyloxy-tetrahydro-2H-pyran-2-yl]prop-1-enyl)(1,3-oxazol-2-yl)]methyl-4-methoxy-6-triethylsilyloxymethyl-tetrahydro-2H-pyran-2-ol(296785-20-1)

Safety Data

• Hazardous Substances Data: 296785-20-1(Hazardous Substances Data)

Upstream product

• 310883-82-0 {(2R,3R,4R,5S,6R)-2-Hydroxy-3,5-dimethyl-6-[(E)-1-methyl-2-(2-methyl-oxazol-4-yl)-vinyl]-4-triphenylsilanyloxy-tetrahydro-pyran-2-yl}-acetic acid tert-butyl ester 
• 310883-83-1 tert-butyl 2-{6-[(E)-1-methyl-2-(2-methyl(oxaszol-4-yl))vinyl](3S,4S,2R,5S,6R)-3,5-dimethyl-4-(triphenylsilyloxy)-tetrahydro-2H-pyran-2-yl}acetate 
• 310883-84-2 2-{6-[(E)-1-methyl-2-(2-methyl(oxazol-4-yl))vinyl](2R,3S,4S,5S,6R)-3,5-dimethyl-4-(triphenylsilyloxy)-tetrahydro-2H-pyran-2-yl}-ethan-1-ol 
• 310883-81-9 6-[(E)-1-methyl-2-(2-methyl(oxazol-4-yl))vinyl](5S,3R,4R,6R)-3,5-dimethyl-4-(triphenylsilyloxy)-tetrahydro-2H-pyran-2-one 
• 310883-80-8 (E)-3-[(2R,3R,4R,5R)-3,5-dihydroxy-7-(2-methyl(oxazol-4-yl))-1-oxo-2,4,6-trimethyl-6-heptenyl]-(4R)-benzyl-2-oxazolidinone 
• 296785-16-5 (4R,6R)-6-(benzyloxymethyl)-4-methoxy-tetrahydro-2H-pyran-2-one 
• 296785-14-3 (6R)-4-methoxy-6-(benzyloxymethyl)-5,6-dihydro-2H-pyran-2-one 
• 310883-86-4 (4R,6R)-6-hydroxymethyl-4-methoxy-tetrahydro-2H-pyran-2-one 
• 215876-09-8 (3R,5R)-6-benzyloxy-3,5-dihydroxy-hexanoic acid tert-butyl ester 
• 147849-63-6 tert-butyl (5R)-3-oxo-5-hydroxy-6-benzyloxyhexanoate 
• 153255-54-0 (4R,6R)-6-Benzyloxymethyl-4-hydroxy-tetrahydro-pyran-2-one 
• 101712-01-0 (R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-2-methylpentane-1,3-dione 
• 139630-91-4 (E)-2-methyl-3-(2-methyloxazol-4-yl)acrylaldehyde 
• 76-86-8 Triphenylsilyl chloride 

Downstream Products

• 310883-88-6 (2R,4R,6R)-2-[4-((E)-2-[(2R,3S,4S,5S,6R)-3,5-dimethyl-6-[2-(trimethylsilyloxyethyl)]-4-(triphenylsilyloxy)-tetrahydro-2H-pyran-2-yl]prop-1-enyl)(1,3-oxazol-2-yl)]-methyl-4-methoxy-2-(triethylsilyloxy)-6-(triethylsilyloxymethyl)-tetrahydro-2H-pyran-2-ol 

Relevant articles and documents

Asymmetric synthesis of phorboxazole B - Part I: Synthesis of the C20-C38 and C39-C46 subunits

The total synthesis of the antitumor marine macrolide phorboxazole B (1) has been realized. The phorboxazoles are representative of a new structural class of macrolides and are among the most cytostatic natural products known: inhibiting the growth of tum