29701-42-6

Basic information

• Product Name: L-Alaninamide, N-acetyl-L-tyrosyl-
• Synonyms: L-Alaninamide,N-acetyl-L-tyrosyl
• CAS NO: 29701-42-6
• Molecular Formula: C14H19N3O4
• Molecular Weight: 293.323
• Mol File: 29701-42-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 723.7±60.0 °C(Predicted)
• Density: 1.258±0.06 g/cm3(Predicted)
• CAS DataBase Reference: L-Alaninamide, N-acetyl-L-tyrosyl-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alaninamide, N-acetyl-L-tyrosyl-(29701-42-6)
• EPA Substance Registry System: L-Alaninamide, N-acetyl-L-tyrosyl-(29701-42-6)

Safety Data

• Hazardous Substances Data: 29701-42-6(Hazardous Substances Data)

Upstream product

• 840-97-1 N-acetyl-L-tyrosine ethyl ester 
• 4726-84-5 alanine amide 
• 7324-05-2 L-alanine amide 

Downstream Products

• 56272-47-0 N-acetyltyrosyl-alanine 

Relevant articles and documents

Determination of the Enantioselectivity for Kinetically Controlled Condensations Catalysed by Amidases and Peptidases

For kinetically controlled synthetic reactions catalysed by amidases and peptidases, the enantio- or stereoselectivity determined from initial rates with racemic mixtures (Esyn, rac) was found to differ from the enantioselectivity determined from measurements with isolated enantiomeric nucleophiles (Esyn). This was observed for kinetically controlled condensation of R-phenyglycineamide with S-, R- and racemic Phe and S-, R- and racemic Leu catalysed by penicillin amidase from E. coli and for kinetically controlled condensation of Nα-acetyl-S-tyrosine ethyl ester with S-, R- and racemic AlaNH2 catalysed by bovine α-chymotrypsin. It is shown that only Esyn, rac determined with racemic nucleophiles is an intrinsic enzyme property which should be used to study the influence of the primary structure, physicochemical parameters and immobilisation on biocatalyst enantioselectivity in kinetically controlled synthetic reactions catalysed by these enzymes.