29706-75-0Relevant academic research and scientific papers
INHIBITORS OF ADENYLATE-FORMING ENZYME MENE
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Paragraph 0428, (2020/08/22)
Provided herein are compounds of Formula (I) and pharmaceutically acceptable salts or tautomers thereof which may inhibit adenylate-forming enzymes. Also provided are pharmaceutical compositions, kits, uses, and methods involving the inventive compounds for the treatment and/or prevention of an infectious disease (e.g., bacterial infection (e.g., tuberculosis, methicillin- resistant Staphylococcus aureus)).
Phosphonoacetic acid derivatives of nucleosides
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, (2008/06/13)
Phosphonoacetic acid derivatives of purine and pyrimidine nucleosides are novel antiviral and/or antineoplastic agents.
Analogues of S adenosylhomocysteine as potential inhibitors of biological transmethylation. Synthesis of analogues with modifications at the 5' thioether linkage
Chang,Coward
, p. 684 - 691 (2007/10/06)
The synthesis of S adenosylhomocysteine analogues, in which the 5' thioether linkage is replaced by an oxygen or nitrogen isostere, has been investigated. These compounds were designed to be resistant to enzyme catalyzed hydrolytic cleavage of the 5' subs
