29712-30-9 Usage
General Description
[(dimethylamino)methylene]bisphosphonic acid, also known as medronic acid, is a chemical compound that belongs to the class of bisphosphonates. It is a synthetic analogue of pyrophosphate and is used for the treatment of osteoporosis, Paget's disease, and hypercalcemia. The compound works by inhibiting the activity of osteoclasts, which are cells responsible for breaking down bone tissue. This helps to prevent bone loss and increase bone density. Medronic acid is administered intravenously and has a long duration of action, making it suitable for treating conditions such as osteoporosis that require long-term management. It is also used in some industrial applications, such as in the prevention of scale formation in water systems. However, it is important to note that medronic acid can have potential adverse effects, including gastrointestinal irritation and renal impairment, so it should be used under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 29712-30-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,7,1 and 2 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 29712-30:
(7*2)+(6*9)+(5*7)+(4*1)+(3*2)+(2*3)+(1*0)=119
119 % 10 = 9
So 29712-30-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H11NO6P2.Tc/c1-4(2)3(11(5,6)7)12(8,9)10;/h3H,1-2H3,(H2,5,6,7)(H2,8,9,10);/q;+4/p-4/i;1+1
29712-30-9Relevant articles and documents
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Fukuda,M. et al.
, p. 1030 (1975)
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Synthesis of new types of aminomethylenediphosphorus-containing acids and their derivatives
Prishchenko,Livantsov,Novikova,Livantsova,Ershov,Petrosyan
, p. 370 - 379 (2015/04/14)
Convenient methods for synthesis of various aminomethylenediphosphorus-containing acids and their derivatives starting from available trimethylsilyl esters of hypophosphorous and phosphorous acids, ethoxymethyleneimine hydrochlorides, and N-substituted formamides have been proposed. Selected properties of the obtained compounds have been examined.
Convenient synthesis of analogs of aminomethylene gem-diphosphonic acid from amines without catalyst
Wu, Mingshu,Chen, Ruyu,Huang, You
, p. 1393 - 1398 (2007/10/03)
A simple, novel, and convenient synthesis of analogs of aminomethylene gem-diphosphonic acids in one-pot from primary and secondary amines in moderate yields was reported without catalyst.
