297150-27-7

Basic information

• Product Name: N-(1H-1,2,3-BENZOTRIAZOL-1-YLMETHYL)-3-CHLORO-4-FLUOROANILINE
• Synonyms: N-(1H-1,2,3-BENZOTRIAZOL-1-YLMETHYL)-3-CHLORO-4-FLUOROANILINE;N-(1H-1,2,3-BENZOTRIAZOL-1-YLMETHYL)-N-(3-CHLORO-4-FLUOROPHENYL)AMINE
• CAS NO: 297150-27-7
• Molecular Formula: C₁₃H₁₀ClFN₄
• Molecular Weight: 276.7
• Mol File: 297150-27-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(1H-1,2,3-BENZOTRIAZOL-1-YLMETHYL)-3-CHLORO-4-FLUOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1H-1,2,3-BENZOTRIAZOL-1-YLMETHYL)-3-CHLORO-4-FLUOROANILINE(297150-27-7)
• EPA Substance Registry System: N-(1H-1,2,3-BENZOTRIAZOL-1-YLMETHYL)-3-CHLORO-4-FLUOROANILINE(297150-27-7)

Safety Data

• Hazardous Substances Data: 297150-27-7(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 50-00-0 formaldehyd 
• 367-21-5 3-chloro-4-fluorophenylamine 

Downstream Products

• 77898-24-9 3-chloro-4-fluoro-N-methylaniline 
• 1240693-60-0 C₁₇H₁₀ClF₂N₃ 

Relevant articles and documents

Synthesis and cytotoxicity studies of quinoline-3-carbonitrile derivatives

A series of quinoline-3-carbonitrile derivatives were designed and synthesized. Their cytotoxicity in vitro against four cancer cell lines (A549, HT-29, MDA-MB-231 and SMMC-7721) were evaluated by standard MTT assay. The pharmacological results showed that most of the prepared compounds displayed excellent selective cytotoxicity toward SMMC-7721 cell line. Among them, compounds 7c, 7e, 11b, 11f and 11g were more active than Gefitinb against SMMC-7721 cell line.