297170-22-0Relevant academic research and scientific papers
Tert-butyldiphenylsilylmethyl triflate: Preparation and dipolar cycloaddition reactions of 1-(tert-butyldiphenylsilylmethyl)-6-cyano-4-methyl-1,2,5,6-tetrah ydropyridine
Hart, David J.,Huang, Ying
, p. 3203 - 3213 (2007/10/03)
Alkylation of substituted pyridines with tert-butyldiphenylsilylmethyl triflate provides N-[tert-butyldiphenylsilylmethyl]pyridinium triflates in excellent yields. Reductive cyanation of the pyridinium triflates provides 1-(tert-butyldiphenylsilylmethyl)-6-cyano-1,2,5,6-tetrahydropyrid ines, azomethine ylid precursors, in modest yields. An unexpected dipolar cycloaddition reaction of an ylid derived from the title 6-cyanopiperidine is described.
