297179-21-6

Basic information

• Product Name: 2-Phenanthrenol, 10-ethoxy-4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, acetate, (4bS,8aS,10R)-
• Synonyms: 2-Phenanthrenol, 10-ethoxy-4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, acetate, (4bS,8aS,10R)-
• CAS NO: 297179-21-6
• Molecular Formula: C24H36 O3
• Molecular Weight: 0
• Mol File: 297179-21-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Phenanthrenol, 10-ethoxy-4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, acetate, (4bS,8aS,10R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenanthrenol, 10-ethoxy-4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, acetate, (4bS,8aS,10R)-(297179-21-6)
• EPA Substance Registry System: 2-Phenanthrenol, 10-ethoxy-4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-, acetate, (4bS,8aS,10R)-(297179-21-6)

Safety Data

• Hazardous Substances Data: 297179-21-6(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 54146-29-1 7α,13-diacetoxy-totara-8,11,13-triene 

Downstream Products

• 297179-10-3 7α-ethoxytotara-8,11,13-trien-13-ol 

Relevant articles and documents

The synthesis and antibacterial activity of totarol derivatives. Part 3: modification of ring-B

Ring-B derivatization of totarol (1) afforded the series of compounds 2-22 which were screened in vitro against: β-lactamase-positive and high level gentamycin-resistant Enterococcus faecalis, penicillin-resistant Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus (MRSA), and multiresistant Klebsiella pneumoniae. Several of the derivatives retained much of the antibacterial activity of totatol against the first three of these organisms (all Gram-positive), but none was more active. The Gram-negative Klebsiella was resistant to all compounds examined. Totarol (1) was shown to uncouple oxidative phosphorylation in isolated mitochondria at 50 μM. Copyright (C) 2000 Elsevier Science Ltd.