2972-05-6Relevant articles and documents
β-lactam synthesis via copper-catalyzed directed aminoalkylation of unactivated alkenes with cyclobutanone O-benzoyloximes
Zhang, Heng,Lv, Xiaoyan,Yu, Hanrui,Bai, Zibo,Chen, Gong,He, Gang
, p. 3620 - 3625 (2021)
A new protocol for amide-directed Cu-catalyzed aminoalkylation of unactivated alkenes using cyclobutanone oxime esters as alkyl radical donors is developed. Both primary and secondary alkyl groups can be selectively installed at the C4 position of termina
Synthesis of β-nitro ketones from geminal bromonitroalkanes and silyl enol ethers by visible light photoredox catalysis
Cao, Haoying,Ma, Shanshan,Feng, Yanhong,Guo, Yawen,Jiao, Peng
supporting information, p. 1780 - 1783 (2022/02/17)
Various β-nitro ketones, including those bearing a β-tertiary carbon, were prepared from geminal bromonitroalkanes and trimethylsilyl enol ethers of a broad range of ketones by visible light photoredox catalysis, which were then easily converted into β-amino ketones, 1,3-amino alcohols, α,β-unsaturated ketones, β-cyano ketones and γ-nitro ketones.
Enantioselective Iridium-Catalyzed Allylation of Nitroalkanes: Entry to β-Stereogenic α-Quaternary Primary Amines
Jung, Woo-Ok,Mai, Binh Khanh,Spinello, Brian J.,Dubey, Zachary J.,Kim, Seung Wook,Stivala, Craig E.,Zbieg, Jason R.,Liu, Peng,Krische, Michael J.
supporting information, p. 9343 - 9349 (2021/07/19)
The first systematic study of simple nitronate nucleophiles in iridium-catalyzed allylic alkylation is described. Using a tol-BINAP-modified π-allyliridiumC,O-benzoate catalyst, α,α-disubstituted nitronates substitute racemic branched alkyl-substituted al
