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Usage

Uses

Used in Pharmaceutical Industry:
((3-FLUOROPHENYL)METHYLENE)METHANE-1,1-DICARBONITRILE is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, ((3-FLUOROPHENYL)METHYLENE)METHANE-1,1-DICARBONITRILE is utilized as a key intermediate for the production of agrochemicals, aiding in the creation of effective pest control solutions and other agricultural products.
Used in Dye and Pigment Industry:
((3-FLUOROPHENYL)METHYLENE)METHANE-1,1-DICARBONITRILE is employed as a precursor in the manufacturing process of dyes and pigments, enabling the production of a wide array of colorants for various applications.
Used in Material Science:
((3-FLUOROPHENYL)METHYLENE)METHANE-1,1-DICARBONITRILE has potential applications in the development of novel materials, where it can be used to create innovative substances with unique properties for diverse industries.
Used in Biological Research:
((3-FLUOROPHENYL)METHYLENE)METHANE-1,1-DICARBONITRILE also finds utility in biological research, where it can be employed as a tool to study various biological processes and develop new research methodologies.

Upstream product

• 456-47-3 3-fluoro-benzenemethanol 
• 109-77-3 malononitrile 
• 456-48-4 3-Fluorobenzaldehyde 

Downstream Products

• 94988-88-2 7‐amino‐5‐(3‐fluorophenyl)‐6-cyano‐5H‐pyrano[2,3‐d]pyrimidin‐(1H,3H)-2,4‐dione 
• 111861-40-6 2-Amino-3-cyano-7-amino-4-(3-fluorophenyl)-4H-chromene 
• 226547-93-9 3-(3-fluoro-phenyl)-2,3-dihydro-benzo[f]chromen-1-one 
• 132664-69-8 (2R,3R,10bS)-1,1-Dicyano-2-(3-fluoro-phenyl)-1,2,3,10b-tetrahydro-pyrrolo[2,1-a]isoquinoline-3-carboxylic acid amide 
• 132664-74-5 (2R,3R,10bS)-3-Benzoyl-2-(3-fluoro-phenyl)-2,3-dihydro-10bH-pyrrolo[2,1-a]isoquinoline-1,1-dicarbonitrile 
• 1350892-61-3 C₁₇H₁₀F₂N₂O 
• 111861-27-9 2-amino-3-cyano-(3′-fluorophenyl)-7-hydroxy-4H-chromene 
• 127723-01-7 1-Amino-3,5-di(3-fluorophenyl)-2,4,4,6,6-pentacyano-1-cyclohexene 
• 84186-25-4 2-amino-4-(3-fluorophenyl)-3-cyano-4H-naphtho<2,1-b>pyran 
• 89607-36-3 6-Amino-4-(3-fluoro-phenyl)-3-methyl-1,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile 
• 94639-07-3 6-Amino-4-(3-fluoro-phenyl)-2,2-dimethyl-4H-[1,3]dithiine-5-carbonitrile 
• 103868-27-5 4-(3-Fluoro-phenyl)-6-methyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile 
• 107752-98-7 2-amino-4-(3-fluorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 
• 107752-90-9 2-amino-4-(3-fluorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 

Relevant academic research and scientific papers

Kinetically Controllable Pd-Catalyzed Decarboxylation Enabled [5 + 2] and [3 + 2] Cycloaddition toward Carbocycles Featuring Quaternary Carbons

A decarboxylative protocol has been developed toward a range of carbocycles. The key success is based on the use of a batch of newly designed cyclic carbonates as substrates that can provide carbon-carbon zwitterion intermediate under palladium catalysis.

Metal-free multicomponent synthesis of novel macrocyclic tetrathiadienes with cyano and amino groups

The first synthesis of 5,12-diamino-7,14-bis(aryl)-1,4,8,11-tetrathiacyclotetradeca-5,12-diene-6,13-dicarbonitriles was performed as a multicomponent macroheterocyclization of malononitrile, aryl aldehydes, and 1,2-ethanedithiol in the presence of a catal

Discovery of Highly Potent Adenosine A1Receptor Agonists: Targeting Positron Emission Tomography Probes

Adenosine receptor (AR) radiotracers for positron emission tomography (PET) have provided knowledge on the in vivo biodistribution of ARs in the central nervous system (CNS), which is of therapeutic interest for various neuropsychiatric disorders. Additio

Phosphine-Catalyzed (4 + 2) Annulation of δ-Sulfonamido-Substituted Enones with 1,1-Dicyanoalkenes: Synthesis of Piperidine Derivatives

The δ-sulfonamido-substituted enones were employed as phosphine acceptor in phosphine-catalyzed (4 + 2) annulation of 1,1-dicyanoalkenes. They served as a four-membered synthon to react with 1,1-dicyanoalkenes under mild reaction conditions, producing pip

Manganese-organic framework assembled by 5-((4′-(tetrazol-5″-yl)benzyl)oxy)isophthalic acid: A solvent-free catalyst for the formation of carbon–carbon bond

A new three-dimensional manganese-based metal–organic framework Mn4L2(HL)(H2O)5, (1), based on semi-rigid 5-((4′-(tetrazol-5′’-yl)benzyl)oxy)isophthalic acid ligand (H3L) have been prepared and charac

Synthesis, structure, and catalytic properties of a copper(II) coordination polymer material constructed from 5-nitro-1,2,3-benzenetricarboxylic acid and bis(4-pyridylformyl)piperazine mixed ligands

One three-dimensional coordination polymer material, {[Cu3(nbta)2(bpfp)2(H2O)2](H2O)2}n (H3nbta = 5-nitro-1,2,3-benzenetricarboxylic acid, bpfp = bis(4-pyri

Unexpected polymorphism during a catalyzed mechanochemical Knoevenagel condensation

The transformation of a base-catalyzed, mechano-assisted Knoevenagel condensation of mono-fluorinated benzaldehyde derivatives (p-, m-, o-benzaldehyde) with malonodinitrile was investigated in situ and in real time. Upon milling, the para-substituted prod

Construction of two Zn(ii)/Cd(ii) multifunctional coordination polymers with mixed ligands for catalytic and sensing properties

With the purpose of exploring the catalytic and sensing properties of crystalline materials, two coordination polymers were rationally constructed by the reactions of Zn(ii)/Cd(ii) ions with methyl-3-hydroxy-5-carboxy-2-thiophenecarboxylate (H2

Stereoselective one-pot synthesis of polycyanosubstituted piperidines

Abstract: An effective and facile multicomponent method for the synthesis of polysubstituted piperidines is described. The Michael–Mannich type cascade of benzylidenemalononitriles with aromatic aldehydes and ammonium acetate or aqueous ammonia provides c

N-heterocyclic carbene-promoted [3+2] cycloaddition of allenyl sulfone and arylidenemalononitriles

N-Heterocyclic carbenes promote the [3+2] cycloaddition of allenyl sulfone and arylidenemalononitriles, accompanied by 1,2-migration of the sulfonyl group. This reaction provides a new route to highly substituted cyclopentenes.