297756-31-1 Usage
Uses
Used in Pharmaceutical Industry:
5-Amino-1-BOC-benzoimidazole is used as a versatile building block in organic synthesis for the synthesis of various bioactive compounds. Its properties and reactivity make it useful in the creation and modification of potential drug candidates, contributing to the development of new therapeutic agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-Amino-1-BOC-benzoimidazole serves as a key intermediate in the synthesis of complex organic molecules with potential pharmaceutical applications. Its presence in these molecules can influence their biological activity and pharmacological properties, making it an essential component in drug discovery and optimization processes.
Used in Material Science:
5-Amino-1-BOC-benzoimidazole also has applications in material science, where it can be incorporated into the design and synthesis of novel materials with specific properties. Its unique chemical structure allows for the development of materials with tailored characteristics, such as improved stability, reactivity, or selectivity, which can be beneficial in various applications.
Used in Agrochemical Research:
In agrochemical research, 5-Amino-1-BOC-benzoimidazole is utilized for the synthesis of bioactive compounds with potential applications in agriculture. These compounds can be used as pesticides, herbicides, or other agrochemicals to protect crops and enhance agricultural productivity. 5-AMINO-1-BOC-BENZOIMIDAZOLE's reactivity and versatility make it a valuable tool in the development of new and effective agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 297756-31-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,7,7,5 and 6 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 297756-31:
(8*2)+(7*9)+(6*7)+(5*7)+(4*5)+(3*6)+(2*3)+(1*1)=201
201 % 10 = 1
So 297756-31-1 is a valid CAS Registry Number.
297756-31-1Relevant academic research and scientific papers
Structure-activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl)propyl thiourea template
Lee, Jeewoo,Tran, Phuong-Thao,Hoang, Van-Hai,Thorat, Shivaji A.,Kim, Sung Eun,Ann, Jihyae,Chang, Yu Jin,Nam, Dong Woo,Song, Hyundong,Mook-Jung, Inhee,Lee, Jiyoun
, p. 3821 - 3830 (2013/07/19)
In an effort to design inhibitors of human glutaminyl cyclase (QC), we have synthesized a library of N-aryl N-(5-methyl-1H-imidazol-1-yl)propyl thioureas and investigated the contribution of the aryl region of these compounds to their structure-activity relationships as cyclase inhibitors. Our design was guided by the proposed binding mode of the preferred substrate for the cyclase. In this series, compound 52 was identified as the most potent QC inhibitor with an IC50 value of 58 nM, which was two-fold more potent than the previously reported lead 2. Compound 52 is a most promising candidate for future evaluation to monitor its ability to reduce the formation of pGlu-Aβ and Aβ plaques in cells and transgenic animals.
3-(anilinomethylene) oxindoles
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Page column 50-51, (2010/02/04)
The present invention relates generally to novel amine substituted oxindole compounds and compositions. Such compounds and compositions have utility as pharmacological agents in treating diseases or conditions alleviated by the inhibition or antagonism of
