29784-22-3

Basic information

• Product Name: 3-(4-methoxyphenyl)-1-(thiophen-2-yl)prop-2-yn-1-one
• Synonyms: 3-(4-methoxyphenyl)-1-(thiophen-2-yl)prop-2-yn-1-one
• CAS NO: 29784-22-3
• Molecular Weight: 242.298
• Mol File: 29784-22-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenyl)-1-(thiophen-2-yl)prop-2-yn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-1-(thiophen-2-yl)prop-2-yn-1-one(29784-22-3)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-1-(thiophen-2-yl)prop-2-yn-1-one(29784-22-3)

Safety Data

• Hazardous Substances Data: 29784-22-3(Hazardous Substances Data)

Upstream product

• 5271-67-0 2-Thiophenecarbonyl chloride 
• 768-60-5 4-methoxyphenylacetylen 

Downstream Products

• 1018459-44-3 [3,5-bis(4-methoxyphenyl)isoxazol-4-yl](thiophen-2-yl)methanone 
• 1354049-04-9 (3aS,4S,5aR,11aR,11bS)-4-methoxy-10-(4-methoxyphenyl)-2,2-dimethyl-8-(2-thienyl)-3a,4,5a,6,11a,11b-hexahydro[1,3]dioxolo[4,5]pyrano[3,2-b][1,5]oxazocine 
• 1354048-96-6 (2R)-2-[(3aR,5S,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl]-7-(4-methoxyphenyl)-5-(2-thienyl)-2,3-dihydro-1,4-oxazepine 
• 106110-67-2 Diethyl-dithiocarbamic acid (E)-1-(4-methoxy-phenyl)-3-oxo-3-thiophen-2-yl-propenyl ester 

Relevant articles and documents

C-C Bond Cleavage Initiated Cascade Reaction of β-Enaminones: One-Pot Synthesis of 5-Hydroxy-1 H-pyrrol-2(5 H)-ones

An unprecedented C(CO)-C(Ar) bond cleavage of β-enaminones has been realized under mild and transition-metal-free conditions. The cascade transformation based on this C-C bond cleavage involves 1,3-O/C migration and aerobic hydroxylation and leads to various 5-hydroxy-1H-pyrrol-2(5H)-ones with broad functional group tolerance. The application of this methodology has been showcased by preparing 5-alkoxy-1H-pyrrol-2(5H)-one derivatives and a pyrrolo[2,1-a]isoquinolin-3-one derivative.

Novel microwave-assisted one-pot synthesis of isoxazoles by a three-component coupling-cycloaddition sequence

The consecutive Sonogashira coupling of acid chlorides with terminal alkynes, followed by 1,3-dipolar cycloaddition under dielectric heating of in situ generated nitrile oxides from hydroximinoyl chlorides furnishes isoxazoles in moderate to good yields i