29786-46-7

Upstream product

• 28049-60-7 1-(3-chlorophenyl)cyclobutane carbonitrile 
• 1529-41-5 3-chloro-benzeneacetonitrile 

Downstream Products

• 29786-56-9 <1-(m-Chlorophenyl)-cyclobutyl>-carbonylisocyanat 
• 959140-89-7 1-(3-chlorophenyl)cyclobutane-1-amine hydrochloride 
• 374588-99-5 5-(3-chlorophenyl)-3,4-dihydro-2H-pyrrole 
• 29786-29-6 (<1-(m-Chlorophenyl)cyclobutyl>carbonyl)carbamsaeureethylester 
• 29771-04-8 (<1-(m-Chlorophenyl)cyclobutyl>carbonyl)carbamsaeuremethylester 
• 29770-32-9 (<1-(m-Chlorophenyl)-cyclobutyl>-carbonyl)-harnstoff 

Relevant academic research and scientific papers

Oxadiazole Amine Derivative Compounds as Histone Deacetylase 6 Inhibitor, and the Pharmaceutical Composition Comprising the same

The present invention relates to a novel compound having an activity of inhibiting histone deacetylase 6 (HDAC6), an optical isomer thereof or a pharmaceutically acceptable salt thereof, a use thereof for preparation of a drug for treatment, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing the same. The novel compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof according to the present invention has an activity of inhibiting histone deacetylase 6 (HDAC6), and is effective for preventing or treating HDAC6-related diseases, including infectious diseases; neoplasm; endocrine, nutritional and metabolic diseases; mental and behavior disorders; nerve disorders; eye and adnexa diseases; cardiovascular diseases; respiratory diseases; digestive organ diseases; skin and subcutaneous tissue diseases; musculoskeletal and connective tissue diseases; or congenital malformation, deformation and chromosomal abnormality.COPYRIGHT KIPO 2017