29786-48-9

Upstream product

• 31938-07-5 (3-bromophenyl)acetonitrile 
• 29786-38-7 1-(3-bromophenyl)cyclobutane-1-carbonitrile 

Downstream Products

• 29786-59-2 <1-(m-Bromophenyl)-cyclobutyl>-carbonylisocyanat 
• 29770-35-2 (<1-(m-Bromophenyl)-cyclobutyl>-carbonyl)-harnstoff 
• 29786-18-3 (<1-(m-Bromophenyl)cyclobutyl>carbonyl)carbamsaeuremethylester 
• 29786-30-9 (<1-(m-Bromophenyl)cyclobutyl>carbonyl)carbamsaeureethylester 

Relevant academic research and scientific papers

Oxadiazole Amine Derivative Compounds as Histone Deacetylase 6 Inhibitor, and the Pharmaceutical Composition Comprising the same

The present invention relates to a novel compound having an activity of inhibiting histone deacetylase 6 (HDAC6), an optical isomer thereof or a pharmaceutically acceptable salt thereof, a use thereof for preparation of a drug for treatment, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing the same. The novel compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof according to the present invention has an activity of inhibiting histone deacetylase 6 (HDAC6), and is effective for preventing or treating HDAC6-related diseases, including infectious diseases; neoplasm; endocrine, nutritional and metabolic diseases; mental and behavior disorders; nerve disorders; eye and adnexa diseases; cardiovascular diseases; respiratory diseases; digestive organ diseases; skin and subcutaneous tissue diseases; musculoskeletal and connective tissue diseases; or congenital malformation, deformation and chromosomal abnormality.COPYRIGHT KIPO 2017