298-50-0 Usage
Uses
Used in Ophthalmology:
PROPARACAINE is used as a topical anesthetic for [application reason] to provide temporary relief from discomfort and pain associated with eye conditions such as corneal abrasions, foreign body removal, and diagnostic procedures.
Used in Pharmaceutical Industry:
PROPARACAINE is used as an active pharmaceutical ingredient for [application reason] to formulate eye drops and other ophthalmic solutions that help alleviate eye discomfort and pain.
Used in Veterinary Medicine:
PROPARACAINE is used as a veterinary anesthetic for [application reason] to provide temporary pain relief during diagnostic and surgical procedures in animals.
Brand Name:
PROPARACAINE is available under the brand name Pro-Banthine (Searle), which is specifically formulated for treating stomach ulcers. However, it is important to note that this brand name is associated with Propantheline, a different compound, and not directly related to PROPARACAINE.
Pharmacology
The pharmacological action of propantheline is qualitatively similar to atropine. It has a
weaker effect on the CNS than atropine. Unlike atropine, it exhibits greater ganglioblocking action than antimuscarinic action. Moreover, upon overdose it causes neuromuscular
curare-like blockage.
Synthesis
Propanetheline, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-
ylcarbonyl) oxy]ethyl]-2-propanaminium bromide (14.1.11), is synthesized by reacting xanthen-9-carboxylic acid chloride with 2-di-iso-propylaminoethanol, giving the ester (14.1.10),
which upon reaction with methylbromide turns into the quaternary salt, propantheline
(14.1.11) [12,13].
Veterinary Drugs and Treatments
Proparacaine is a rapid acting topical anesthetic useful for a variety
of ophthalmic procedures including tonometry (intraocular pressure
measurement), relief of corneal pain to facilitate examination,
biopsy/sample collection, and to distinguish between corneal and
uveal pain. Proparacaine primarily anesthetizes the cornea; with
limited penetration into conjunctiva. Anesthesia is of short duration
(5 – 10 minutes).
Check Digit Verification of cas no
The CAS Registry Mumber 298-50-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,9 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 298-50:
(5*2)+(4*9)+(3*8)+(2*5)+(1*0)=80
80 % 10 = 0
So 298-50-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1
