2981-86-4

Upstream product

• 141-43-5 ethanolamine 
• 83-34-1 3-Methylindole 

Downstream Products

• 14663-53-7 3-carboxymethyl-3,4-dihydro-4(1H)-quinazolinone 
• 54368-19-3 3-methoxycarbonylmethyl-3,4-dihydro-4(1H)-quinazoline 
• 2940-68-3 3-(2-Chloroethyl)-4(3H)-quinazolinone 
• 1367624-57-4 3-(2-(4-(3-(trifluoromethyl)phenyl)piperazine-1-yl)ethyl)quinazoline-4(3H)-one 
• 1367624-81-4 3-(2-(4-(3-(trifluoromethyl)phenyl)piperazine-1-yl)ethyl)quinazoline-4(3H)-one hydrochloride 

Relevant academic research and scientific papers

Selective Oxidative Cleavage of 3-Methylindoles with Primary Amines Affording Quinazolinones

A selective functionalization of C-C-C bonds toward N-C-O bonds is realized by an n-Bu4NI-catalyzed reaction of 3-methylindoles with primary amines using TBHP as the unique oxidant. The systematic process involves oxygenation, nitrogenation, ring-opening, and recyclization, affording a broad range of quinazolinones in good to excellent yields.

Polycyclic N-heterocyclic compounds. Part 601): Reactions of 3-(2-cyanophenyl)quinazolin-4(3H)-ones with primary amines

The reaction of 3-(2-cyanophenyl)quinazolin-4(3H)-one with various primary alkylamines gave 3-alkylquinazolin-4(3H)-ones via an addition of the nucleophile, ring opening, and ring closure (ANRORC) mechanism. This type of reaction required hydroxy group fu