298189-53-4

Basic information

• Product Name: 1,8-Naphthyridine-4-carboxylic acid, 2-phenyl-
• Synonyms: 1,8-Naphthyridine-4-carboxylic acid, 2-phenyl-;2-phenyl-1,8-naphthyridine-4-carboxylic acid
• CAS NO: 298189-53-4
• Molecular Formula: C₁₅H₁₀N₂O₂
• Molecular Weight: 250.2521
• Mol File: 298189-53-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 145 °C(Solv: ethanol (64-17-5))
• Boiling Point: 470.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.332±0.06 g/cm3(Predicted)
• PKA: 0.04±0.10(Predicted)
• CAS DataBase Reference: 1,8-Naphthyridine-4-carboxylic acid, 2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-Naphthyridine-4-carboxylic acid, 2-phenyl-(298189-53-4)
• EPA Substance Registry System: 1,8-Naphthyridine-4-carboxylic acid, 2-phenyl-(298189-53-4)

Safety Data

• Hazardous Substances Data: 298189-53-4(Hazardous Substances Data)

Usage

Class

Naphthyridine carboxylic acids

Structural feature

Contains a phenyl group

Application

Pharmaceutical research and drug development

Potential use

Building block for new drugs or as a pharmacophore in the design of bioactive molecules

Studied for

Antiviral and antibacterial properties

Investigated for

Treatment of various diseases and conditions

Importance

Significant molecule in medicinal chemistry research

Relevant articles and documents

SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE

The present invention relates to nitrogen-containing compounds according to formula (I) and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic ? cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.