29820-45-9Relevant academic research and scientific papers
INTRAMOLECULAR CYCLOADDITIONS OF ARYLKETENES WITH ALKENES. REACTIONS OF 5-ARYLBICYCLOHEPTAN-6-ONES.
Snider, Barry B.,Niwa, Maho
, p. 3175 - 3178 (2007/10/02)
Intramolecular cycloadditions of arylketenes 4 proceed in excellent yield to give 5-arylbicycloheptan-6-ones 5.Reaction of 5a with KOH in THF gives a 95:5 mixture of 7 and 10.Reaction of 5a with KOEt in ETOH give a 1:3 mixture of 7 and 10.Reaction of 5a with vinyllithium and treatment of the resulting alcohol 23 with KH gives the 1,3-sigmatropic rearrangement product 25.
