298220-99-2

Basic information

• Product Name: 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
• Synonyms: 11-Fluoro Desloratadine;8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;Desloratadine EP Impurity A;4-[(11RS)-8-chloro-11-fluoro-6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b]pyridin-11-yl]piperidine
• CAS NO: 298220-99-2
• Molecular Formula: C19H20ClFN2
• Molecular Weight: 330.8269032
• Product Categories: Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 298220-99-2.mol

Chemical Properties

• Boiling Point: 426.9±45.0 °C(Predicted)
• Appearance: /
• Density: 1.27±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 10.16±0.10(Predicted)
• CAS DataBase Reference: 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine(298220-99-2)
• EPA Substance Registry System: 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine(298220-99-2)

Safety Data

• Hazardous Substances Data: 298220-99-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine is used as an active pharmaceutical ingredient for its antihistaminic activity. It is particularly effective in treating allergic reactions and conditions such as rhinitis, urticaria, and pruritus.
Used in Research and Development:
In the field of research and development, 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine serves as a valuable compound for studying the structure-activity relationship of benzocycloheptapyridine derivatives. This helps in the design and synthesis of new drugs with improved antihistaminic properties and potential therapeutic applications.
Used in Drug Formulation:
8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine is also used in the formulation of various pharmaceutical products, such as tablets, capsules, and syrups, to provide relief from allergic symptoms and improve the quality of life for patients suffering from allergic conditions.