2983-71-3Relevant academic research and scientific papers
Synthesis of 2-hydroxy-5,6-diarylnicotinonitriles and 2-chloro-5,6-diarylnicotinonitriles from β-chloroenones We dedicate this article to the memories of Dr. C. V. Asokan who was a great teacher and an eminent researcher
Krishnaraj,Devaky
, p. 6450 - 6456 (2014)
Vilsmeier-Haack reaction of β-ketoaldehydes leads to the formation of β-chloroenones and these chloroenones on treatment with malononitrile afford 2-hydroxy-5,6-diarylnicotinonitriles. But a one-pot reaction of β-ketoaldehydes with Vilsmeier-Haack reagent
A high-yielding protocol for the synthesis of 4,5-diarylpyrimidin-2-amine derivatives from chalcones
Kooramatom Unni, Krishnaraj,Menon, Prasanth K.,George, Scholly Clair,Thomas, Sajesh P.,Devaky
, p. 112 - 118 (2021/10/07)
A novel, high yielding and versatile protocol was achieved for the synthesis of 4,5-diaryl-2-pyrimidinamine derivatives from chalcones. The synthesis was accomplished by converting the chalcones into 3-chloro-2,3-diaryl-2-propen-1-ones followed by subsequent reaction with amidine derivatives.
