29833-93-0

Usage

Dithiane derivative

A dithiane is a chemical compound containing a five-membered ring with two sulfur atoms and two carbon atoms.

Reagent in organic synthesis

2-(2-phenylethylidene)-1,3-dithiane is commonly used as a reagent to help create other organic compounds.

Dithiane functional group

The presence of a dithiane functional group gives the compound unique properties and reactivity.

Phenylethylidene group as a substituent

The phenylethylidene group adds an aromatic and alkene character to the molecule, influencing its chemical properties and reactivity.

Versatile building block

2-(2-phenylethylidene)-1,3-dithiane is used in the synthesis of various organic compounds, such as pharmaceuticals, agrochemicals, and other fine chemicals.

Unique structure and reactivity

The compound's structure and reactivity make it a valuable tool for organic chemists in the development of new molecules and materials.

Upstream product

• 35345-24-5 2-oxo-1,3-dithiane 
• 2612-38-6 1,1-dibromo-2-phenylethane 
• 13411-42-2 2-(trimethylsilyl)-1,3-dithiane 
• 122-78-1 phenylacetaldehyde 
• 95680-48-1 2-[1-(2,2-Dimethyl-propionyloxy)-2-phenyl-ethyl]-[1,3]dithiane-2-carboxylic acid methyl ester 

Downstream Products

• 103-26-4 Methyl cinnamate 
• 107026-68-6 6-[1,3]Dithian-2-ylidene-2,2-dimethyl-5-phenyl-hexan-3-one 
• 107026-72-2 4-[1,3]Dithian-2-ylidene-3-phenyl-butyric acid ethyl ester 
• 107026-75-5 2-(2-Phenyl-pent-4-enylidene)-[1,3]dithiane 
• 72019-00-2 3-benzyl-1,4-dithiepan-2-one 

Relevant academic research and scientific papers

Ketene thioacetals from α-chloromercaptals

Excellent yields of ketene thioacetals are obtained from 2-(1- chloroalkyl)-1,3-dithiolanes or 2-(1-chloroalkyl)-1,3-dithianes.

PREPARATION OF ALKENYL SULFIDES AND ENAMINES BY ALKYLIDENATION OF CARBOXYLIC ACID DERIVATIVES

Treatment of S-alkyl thioesters with a reagent prepared from RCHBr2, Zn, TiCl4, and TMEDA in THF at 25 degC gives Z-alkenyl sulfides selectively in good to excellent yields.Using the alkylidenation method, ketene dithioacetals and enamines are produced fr

Reactions of 1,3-Dithiolan-2-ylium and 1,3-Dithian-2-ylium Tetrafluoroborates and Ambident 2-Styryl Derivatives

The ambident 2-styryl-1,3-dithiolan-2-ylium and 2-styryl-1,3-dithian-2-ylium cations react with preferential carbon-carbon bond formation at the β ethylenic carbon when treated with methylmagnesium iodide.In the lithium aluminium hydride reaction, reduction occurs at either electrophilic carbon center.Methanol and thiophenol react selectively with the β carbon of the side chain.The adduct formation with the heteroatom nucleophiles is readily reversed by acid catalysis.In the absence of the styryl group, the nucleophilic addition is at C-2.Dithioketals of symmetric 1,2-divarbonyl derivatives are readily formed by zinc-induced reductive dimerization of 1,3-dithiolan- and 1,3-dithian-2-ylium salts.

DEALKYLATIVE DECARBOXYLATION.IV. A NOVEL APPROACH TO KETENE THIOACETALS

Reaction of 2-carbomethoxy-1,3-dithiane enolate with an equimolar mixture of trimethylacetyl chloride and an aldehyde followed by dealkylative decarboxylation of the resulting pivalate yields ketene thioacetals.