29871-24-7

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-phenylethyl)pyridinium chloride is used as an active pharmaceutical ingredient for its potential antibacterial and antifungal properties, contributing to the development of new drugs to combat infections.
Used in Chemical Reactions:
Nictine is used as a key component in various chemical reactions, facilitating the synthesis of different compounds and contributing to the advancement of chemical research.
Used in Neurological Disorder Treatment:
1-(2-phenylethyl)pyridinium chloride is used as a potential therapeutic agent for neurological disorders, due to its investigational properties that may help in the treatment of such conditions.
Used in Research and Development:
Nictine is utilized in research and development for its various potential uses, including the exploration of new applications in the pharmaceutical and chemical industries.

InChI:InChI=1/C13H14N.ClH/c1-3-7-13(8-4-1)9-12-14-10-5-2-6-11-14;/h1-8,10-11H,9,12H2;1H/q+1;/p-1

Upstream product

• 110-86-1 pyridine 
• 622-24-2 2-phenylethyl chloride 

Downstream Products

• 1254229-81-6 1-(2-phenylethyl)-1,2,3,6-tetrahydropyridine N-oxide 
• 1254229-82-7 [2,6-⁽²⁾H₂]-1-(2-phenylethyl)-1,2,3,6-tetrahydropyridine 
• 92039-54-8 1-(2-phenylethyl)-1,2,3,6-tetrahydropyridine 

Relevant academic research and scientific papers

Identification of isobaric product ions in electrospray ionization mass spectra of fentanyl using multistage mass spectrometry and deuterium labeling

Isobaric product ions cannot be differentiated by exact mass determinations, although in some cases deuterium labeling can provide useful structural information for identifying isobaric ions. Proposed fragmentation pathways of fentanyl were investigated by electrospray ionization ion trap mass spectrometry coupled with deuterium labeling experiments and spectra of regiospecific deuterium labeled analogs. The major product ion of fentanyl under tandem mass spectrometry (MS/MS) conditions (m/z 188) was accounted for by a neutral loss of N-phenylpropanamide. 1-(2-Phenylethyl)- 1,2,3,6-tetrahydropyridine (1) was proposed as the structure of the product ion. However, further fragmentation (MS3) of the fentanyl m/z 188 ion gave product ions that were different from the product ion in the MS/MS fragmentation of synthesized 1, suggesting that the m/z 188 product ion from fentanyl includes an isobaric structure different from the structure of 1. MS/MS fragmentation of fentanyl in deuterium oxide moved one of the isobars to 1Da higher mass, and left the other isobar unchanged in mass. Multistage mass spectral data from deuterium-labeled proposed isobaric structures provided support for two fragmentation pathways. The results illustrate the utility of multistage mass spectrometry and deuterium labeling in structural assignment of isobaric product ions.