29874-35-9Relevant academic research and scientific papers
Diastereoselective Synthesis of Functionalized Angularly-Fused Tetracycles via an Organocatalytic Quadruple Reaction Sequence
Chang, Fu-Jie,Gurubrahamam, Ramani,Chen, Kwunmin
, p. 1277 - 1282 (2017)
An efficient diastereoselective strategy to access complex structural tetracycles was described through an organocascade quadruple reaction sequence between (E)-2-(3-arylallylidene)-1H-indene-1,3(2H)-diones and β-keto esters. The reaction proceeded throug
1-Indanone and 1,3-indandione Derivatives as Ligands for Misfolded α-Synuclein Aggregates
Sun, Xianwei,Admane, Prasad,Starosolski, Zbigniew A.,Eriksen, Jason L.,Annapragada, Ananth V.,Tanifum, Eric A.
, (2021/11/10)
The development of imaging agents for in vivo detection of alpha-synuclein (α-syn) pathologies faces several challenges. A major gap in the field is the lack of diverse molecular scaffolds with high affinity and selectivity to α-syn fibrils for in vitro s
