299-39-8 Usage
Chemical Properties
Off-White to Pale Yellow Solid
Uses
A class 1a antiarrhythmic agent; a sodium channel blocker.
Check Digit Verification of cas no
The CAS Registry Mumber 299-39-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,9 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 299-39:
(5*2)+(4*9)+(3*9)+(2*3)+(1*9)=88
88 % 10 = 8
So 299-39-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H26N2.H2O4S/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17;1-5(2,3)4/h12-15H,1-11H2;(H2,1,2,3,4)/t12-,13?,14-,15+;/m1./s1
299-39-8Relevant articles and documents
Gram-Scale Synthesis of the (?)-Sparteine Surrogate and (?)-Sparteine
Firth, James D.,Canipa, Steven J.,Ferris, Leigh,O'Brien, Peter
, p. 223 - 226 (2017/12/29)
An 8-step, gram-scale synthesis of the (?)-sparteine surrogate (22 % yield, with just 3 chromatographic purifications) and a 10-step, gram-scale synthesis of (?)-sparteine (31 % yield) are reported. Both syntheses proceed with complete diastereocontrol and allow access to either antipode. Since the syntheses do not rely on natural product extraction, our work addresses long-term supply issues relating to these widely used chiral ligands.