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3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one), also known as Helipyrone A, is an anti-inflammatory natural product related to Arzanol. It is derived from the flowering plant Helichrysum italicum, which is native to the Mediterranean coast. 3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one) exhibits potent anti-inflammatory properties and is characterized by its unique chemical structure, which includes a methylene bridge connecting two pyranone moieties.

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  • 29902-01-0 Structure
  • Basic information

    1. Product Name: 3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one)
    2. Synonyms: 3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one);Helipyrone
    3. CAS NO:29902-01-0
    4. Molecular Formula: C17H20O6
    5. Molecular Weight: 320.13
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 29902-01-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 486 °C at 760 mmHg
    3. Flash Point: 174.9 °C
    4. Appearance: /
    5. Density: 1.292 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one)(29902-01-0)
    11. EPA Substance Registry System: 3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one)(29902-01-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 29902-01-0(Hazardous Substances Data)

29902-01-0 Usage

Uses

Used in Pharmaceutical Industry:
3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one) is used as an anti-inflammatory agent for its ability to reduce inflammation and alleviate pain. Its natural origin and potent anti-inflammatory effects make it a promising candidate for the development of new drugs to treat various inflammatory conditions.
Used in Cosmetic Industry:
In the cosmetic industry, 3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one) is used as an active ingredient in skincare products for its anti-inflammatory and soothing properties. It can help reduce redness, swelling, and discomfort associated with skin irritation, making it suitable for formulations targeting sensitive or inflamed skin.
Used in Nutraceutical Industry:
3,3'-Methylenebis(6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one) is also used in the nutraceutical industry as a dietary supplement for its potential health benefits. It can be incorporated into products aimed at promoting overall health and well-being, particularly in relation to reducing inflammation and supporting the body's natural healing processes.

Check Digit Verification of cas no

The CAS Registry Mumber 29902-01-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,9,0 and 2 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 29902-01:
(7*2)+(6*9)+(5*9)+(4*0)+(3*2)+(2*0)+(1*1)=120
120 % 10 = 0
So 29902-01-0 is a valid CAS Registry Number.

29902-01-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name helipyrone

1.2 Other means of identification

Product number -
Other names 6,6'-diethyl-4,4'-dihydroxy-5,5'-dimethyl-3,3'-methanediyl-bis-pyran-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:29902-01-0 SDS

29902-01-0Downstream Products

29902-01-0Relevant articles and documents

A multicomponent carba-Betti strategy to alkylidene heterodimers-total synthesis and structure-activity relationships of arzanol

Minassi, Alberto,Cicione, Lavinia,Koeberle, Andreas,Bauer, Julia,Laufer, Stefan,Werz, Oliver,Appendino, Giovanni

, p. 772 - 779 (2012/03/27)

Using the synthesis of the heterodimeric phloroglucinyl pyrone arzanol as a benchmark reaction, a carba-version of the Betti multicomponent reaction has been developed. Capitalizing on the fluorous activation of the phenolic component and the use of imini

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