29910-54-1Relevant academic research and scientific papers
Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2′-Deoxyzebularine Embedded in Single-Stranded DNA
Kvach, Maksim V.,Barzak, Fareeda M.,Harjes, Stefan,Schares, Henry A. M.,Kurup, Harikrishnan M.,Jones, Katherine F.,Sutton, Lorraine,Donahue, John,D'Aquila, Richard T.,Jameson, Geoffrey B.,Harki, Daniel A.,Krause, Kurt L.,Harjes, Elena,Filichev, Vyacheslav V.
, p. 1028 - 1035 (2020)
The APOBEC3 (APOBEC3A-H) enzyme family is part of the human innate immune system that restricts pathogens by scrambling pathogenic single-stranded (ss) DNA by deamination of cytosines to produce uracil residues. However, APOBEC3-mediated mutagenesis of vi
